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Browsing Communications by Issue Date

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  • Endy, Drew (2013-03-27)
    Research presentation on recent and unpublished work before the MIT Synthetic Biology Working Group on 24 September 2012 in MIT Building 56.
  • Shetty, Reshma; Lizarazo, Meagan; Rettberg, Randy; Knight, Thomas F., Jr. (Elsevier Inc., 2011-05-20)
    An underlying goal of synthetic biology is to make the process of engineering biological systems easier and more reliable. In support of this goal, we developed BioBrick assembly standard 10 to enable the construction of ...
  • Endy, Drew; Grewal, David; Schultz, Jason; Lynch, Jennifer; Crews, Lee; Fischer, Mark (2010-01-25)
    We present an updated, clean draft for additional public comment of a new legal framework supporting the future of biotechnology. The framework, named here as the BioBrick Public Agreement, is based upon the contribution ...
  • Fischer, Mark; Crews, Lee; Lynch, Jennifer; Schultz, Jason; Grewal, David; Endy, Drew (2009-10-18)
    We present a draft for public comment of a new legal framework supporting the future of biotechnology. The framework, named here as the BioBrick Public Agreement, is based upon the contribution of promises not to assert ...
  • Win, Maung Nyan; Smolke, Christina (2009-07-29)
    This supplement provides additional detail on the data analysis methods and the raw data for the RNA devices presented in the published manuscript and supporting online material. The information provided in the current ...
  • Smolke, CD; Win, MN (2009-06-30)
    We are publishing the following draft correction and clarification to Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14283-8. We are now working directly with the PNAS Editor to have this correction published by the ...
  • Soergel, David; Choi, Kirindi; Thomson, Ty; Doane, Jay; George, Brian; Morgan-Linial, Ross; Brent, Roger; Endy, Drew (2008-06-19)
    We describe an open source software tool called MONOD, for Modeler’s Notebook and Datastore, designed to capture and communicate knowledge generated during the process of building models of many-component biological ...
  • Shetty, Reshma P (2008-05-27)
    The aim of this thesis is to consider how fundamental engineering principles might best be applied to the design and construction of engineered biological systems. I begin by applying these principles to a key application ...
  • Garfinkel, Michele; Endy, Drew; Epstein, Gerald; Friedman, Robert (2007-12-04)
    The following papers were commissioned for the project Synthetic Genomics: Risks and Benefits for Science and Society. These papers formed the basis of many discussions at project workshops and at a large invitational ...
  • Sanghvi, Yogesh (2007-12-04)
    Until recently, the synthesis of DNA has been a tedious, time consuming, expensive and experimentally challenging task. But advances in automated instrumentation and improved chemistry have now made it possible to make ...
  • Jones, Robert (2007-12-04)
    Currently the vast majority of DNA synthesis is performed by service companies or by in-house central facilities in universities and large companies. The DNA synthesis industry provides researchers with custom DNA at ...
  • Furger, Franco (2007-12-04)
    This report is based on the assumption that in Europe and in its member countries—with the exception perhaps of Switzerland—“synthetic genomics” as a distinct policy domain does not yet exist. This conclusion is based ...
  • Fleming, Diane (2007-12-04)
    The ability to synthesize molecules found in living organisms is not new for scientists in the fields of biochemistry and molecular biology. However, the “synthetic biology” made possible by the genetic mapping of ...
  • Collett, Marc (2007-12-04)
    In 2002, a team of researchers at the State University of New York led by Eckard Wimmer assembled a DNA template for the RNA poliovirus using an internet-available nucleotide sequence and mail order synthetic ...
  • Baric, Ralph (2007-12-04)
    Viral disease outbreaks have long inspired fear in human populations. Highly pathogenic infectious disease has shaped world history, primarily by impacting the outcome of wars and other global conflicts and precipitating ...
  • Garfinkel, Michele; Endy, Drew; Epstein, Gerald; Friedman, Robert (2007-10-17)
    Gene and genome synthesis, that is, constructing long stretches of DNA from constituent chemicals, provides scientists with new and unparalleled capabilities both for understanding biology and for using it for beneficial ...
  • Vincent Rouilly, Barry Canton; Poul Nielsen, Richard Kitney (2007-10-04)
    One of the main goals in Synthetic Biology is to assess the feasibility of building novel biological systems from interchangeable and standardized parts. In order to collect and share parts, a Registry of standardized DNA ...
  • Endy, Drew (2007-08-14)
    Biology is a technology for processing information, materials, and energy. As a technology platform, biological systems provide access to artifacts and processes across a range of scales (e.g., the ribosome is a programmable ...
  • Shetty, Reshma P.; Endy, Drew; Knight, Thomas F. Jr (2007-07-17)
    Implementing in vivo information processing is a key challenge in synthetic biology. We describe the construction and characterization of digital transcription-based devices from zinc fingers and leucine zippers. We also ...
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