Now showing items 25-27 of 55

    • Engineering transcription-based digital logic devices 

      Shetty, Reshma P.; Endy, Drew; Knight, Thomas F. Jr (2007-07-17)
      Implementing in vivo information processing is a key challenge in synthetic biology. We describe the construction and characterization of digital transcription-based devices from zinc fingers and leucine zippers. We also ...
    • Analysis of Targeted and Combinatorial Approaches to Phage T7 Genome Generation 

      Mallet, Alex (2007-02-06)
      I performed computational analyses of various approaches to generating re- engineered versions of the genome of bacteriophage T7. I analyzed a proposed design for a re-engineered genome by examining conservation of T7 ...
    • Simulation, Models, and Refactoring of Bacteriophage T7 

      Kosuri, Sriram (2007-02-02)
      Our understanding of why biological systems are designed in a particular way would benefit from biophysically-realistic models that can make accurate predictions on the time-evolution of molecular events given arbitrary ...