Browsing MIT Open Access Articles by Author "Zaborenko, Nikolay"
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Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds
Goodell, John R.; McMullen, Jonathan P.; Zaborenko, Nikolay; Maloney, Jason R.; Ho, Chuan-Xing; e.a. (American Chemical Society, 2009-08)An automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo ... -
Mechanistic Investigations of Epoxide Aminolysis in Microreactors at High Temperatures and Pressures
Zaborenko, Nikolay; Bedore, Matthew W.; Jamison, Timothy F.; Jensen, Klavs F. (American Chemical Society, 2011-01)A continuous-flow microreactor is applied for a kinetic study of a model β-amino alcohol formation by epoxide aminolysis. A large number of experiments are performed in a short time with minimal reagent consumption. The ...