Browsing MIT Open Access Articles by Author "Tabach, Yuval"
Now showing items 1-2 of 2
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High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
Schwartz, Schraga; Mumbach, Maxwell R.; Jovanovic, Marko; Mertins, Philipp; Shishkin, Alexander; e.a. (Elsevier B.V., 2013-11)N[superscript 6]-methyladenosine (m[superscript 6]A) is the most ubiquitous mRNA base modification, but little is known about its precise location, temporal dynamics, and regulation. Here, we generated genomic maps of ... -
Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy
Stupp, Doron; Tabach, Yuval; Suzuki, Hiroshi; Lu, Timothy K; Nissim, Lior; e.a. (Elsevier BV, 2017-10)Despite its success in several clinical trials, cancer immunotherapy remains limited by the rarity of targetable tumor-specific antigens, tumor-mediated immune suppression, and toxicity triggered by systemic delivery of ...