Browsing MIT Open Access Articles by Title
Now showing items 14897-14916 of 55906
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Enantioselective total synthesis of (-)-deoxoapodine
(Wiley, 2017-09-27)The first enantioselective total synthesis of (−)-deoxoapodine is described. Our synthesis of this hexacyclic aspidosperma alkaloid includes an efficient molybdenum-catalyzed enantioselective ring-closing metathesis reaction ... -
Enantioselective Total Synthesis of (−)-Acylfulvene and (−)- Irofulven
(American Chemical Society, 2009-11)We report our full account of the enantioselective total synthesis of (−)-acylfulvene (1) and (−)-irofulven (2), which features metathesis reactions for the rapid assembly of the molecular framework of these antitumor ... -
Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells
(BioMed Central, 2019-02)Background: MicroRNAs are noncoding RNA molecules of ~ 22 nucleotides with diagnostic and therapeutic action [Curr Drug Targets, 2015. 16(12): p. 1381-403], affecting the expression of mRNAs involved in invasion, migration, ... -
Encapsulated Pheochromocytoma Cells Secrete Potent Noncatecholamine Factors
(Mary Ann Liebert, Inc., 2009-07)Pheochromocytomas are widely believed to induce cardiomyopathy via hypersecretion of catecholamines, including norepinephrine (NE). NE can have direct cardiomyocyte toxicity and/or can stimulate myocardial remodeling ... -
Encapsulated Plant-Derived Antimicrobial Reduces Enteric Bacterial Pathogens on Melon Surfaces during Differing Contamination and Sanitization Treatment Scenarios
(Multidisciplinary Digital Publishing Institute, 2021-10-12)This study aimed to quantify survival in <i>Escherichia coli</i> O157:H7 and <i>Salmonella enterica</i> serovar Typhimurium isolates on melon rind surface samples achieved by sanitizer treatment under three differing melon ... -
Encapsulated Plant-Derived Antimicrobial Reduces Enteric Bacterial Pathogens on Melon Surfaces during Differing Contamination and Sanitization Treatment Scenarios
(Multidisciplinary Digital Publishing Institute, 2021-10)This study aimed to quantify survival in <i>Escherichia coli</i> O157:H7 and <i>Salmonella enterica</i> serovar Typhimurium isolates on melon rind surface samples achieved by sanitizer treatment under three differing melon ... -
Encapsulating commercial accelerometers with epoxy and fluoroelastomer for harsh hydrocarbon fluid environment
(Springer Science and Business Media LLC, 2023)<jats:title>Abstract</jats:title><jats:p>Traditionally, in the oil and gas industry, accelerometers are mounted externally on motors for condition monitoring of vertically suspended, closed suction hydrocarbon pumps due ... -
Encapsulation of Pt(IV) prodrugs within a Pt(II) cage for drug delivery
(Royal Society of Chemistry, The, 2014-11)This report presents a novel strategy that facilitates delivery of multiple, specific payloads of Pt(IV) prodrugs using a well-defined supramolecular system. This delivery system comprises a hexanuclear Pt(II) cage that ... -
Encoded Hydrogel Microparticles for Sensitive and Multiplex microRNA Detection Directly from Raw Cell Lysates
(American Chemical Society (ACS), 2016-02)In recent years, microRNAs (miRNAs) have emerged as promising diagnostic markers because of their unique dysregulation patterns under various disease conditions and high stability in biological fluids. However, current ... -
Encoded loop-lanthanide-binding tags for long-range distance measurements in proteins by NMR and EPR spectroscopy
(Springer Netherlands, 2015-09)We recently engineered encodable lanthanide binding tags (LBTs) into proteins and demonstrated their applicability in Nuclear Magnetic Resonance (NMR) spectroscopy, X-ray crystallography and luminescence studies. Here, we ... -
Encoding arbitrary four-qubit states in the spatial parity of a photon pair
(American Physical Society, 2012-06)Advancing quantum information processing is predicated on the preparation of ever-larger multiqubit states. Photonic realizations of such states may be achieved by increasing the number of photons populating the state or ... -
Encoding Cortical Dynamics in Sparse Features
(Frontiers Research Foundation, 2014-05)Distributed cortical solutions of magnetoencephalography (MEG) and electroencephalography (EEG) exhibit complex spatial and temporal dynamics. The extraction of patterns of interest and dynamic features from these cortical ... -
Encoding higher-order structure in visual working memory: A probabilistic model
(Cognitive Science Society, 2010)When encoding a scene into memory, people store both theoverall gist of the scene and detailed information about a few specific objects. Moreover, they use the gist to guide their choice of which specific ... -
Encoding of brain state changes in local field potentials modulated by motor behaviors
(Springer Science + Business Media B.V., 2010-02)Local field potentials (LFPs) measure aggregate neural activity resulting from the coordinated firing of neurons within a local network. We hypothesized that state parameters associated with the underlying brain dynamics ... -
Encoding of vinylidene isomerization in its anion photoelectron spectrum
(American Association for the Advancement of Science (AAAS), 2017-10)inylidene-acetylene isomerization is the prototypical example of a 1,2-hydrogen shift, one of the most important classes of isomerization reactions in organic chemistry. This reaction was investigated with quantum state ... -
Encoding Probabilistic Brain Atlases Using Bayesian Inference
(Institute of Electrical and Electronics Engineers, 2009-06)This paper addresses the problem of creating probabilistic brain atlases from manually labeled training data. Probabilistic atlases are typically constructed by counting the relative frequency of occurrence of labels in ... -
Encoding Through Patterns: Regression Tree–Based Neuronal Population Models
(MIT Press, 2013-08)Although the existence of correlated spiking between neurons in a population is well known, the role such correlations play in encoding stimuli is not. We address this question by constructing pattern-based encoding models ... -
Encounter times of chromatin loci influenced by polymer decondensation
(American Physical Society, 2018-03)The time for a DNA sequence to find its homologous counterpart depends on a long random search inside the cell nucleus. Using polymer models, we compute here the mean first encounter time (MFET) between two sites located ... -
Encouraging collaboration and building Community in Online Asynchronous Professional Development: designing for social capital
(Springer Science and Business Media LLC, 2020-08)This research investigates a design and development approach to improving science teachers’ access to effective professional development (PD) in a fully online, asynchronous environment. Working with a small number of ...
