An Implantable MEMS Drug Delivery Device for Rapid Delivery in Ambulatory Emergency Care

Author(s)
Elman, Noel; Ho Duc, Hong Linh; Cima, Michael J.
Thumbnail
DownloadElman_Implantable MEMS.pdf (453.7Kb)
PUBLISHER_POLICY
Terms of use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. http://www.springerlink.com/help/disclaimer.mpx
Metadata
Show full item record
Abstract
We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD[superscript 3] (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac resuscitation. Experimental results reveal that the IRD3 provides an effective method for rapid delivery without significant drug degradation. Several medical uses and delivery modalities for IRD3 are proposed.
Date issued
2009-01
URI
http://hdl.handle.net/1721.1/49478
Department
MIT Materials Research Laboratory; Massachusetts Institute of Technology. Department of Materials Science and Engineering
Journal
Biomedical Microdevices
Publisher
Springer Netherlands
Citation
N. Elman, H. Ho Duc, and M. Cima, “An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care,” Biomedical Microdevices, vol. 11, Jun. 2009, pp. 625-631.
Version: Author's final manuscript
ISSN
1387-2176
1572-8781
Collections