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Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration

dc.contributor.authorChauhan, Vikash P.
dc.contributor.authorPopovic, Zoran
dc.contributor.authorChen, Ou
dc.contributor.authorCui, Jian
dc.contributor.authorFukumura, Dai
dc.contributor.authorBawendi, Moungi G.
dc.contributor.authorJain, Rakesh K.
dc.date.accessioned2012-08-14T18:06:09Z
dc.date.available2012-08-14T18:06:09Z
dc.date.issued2011-10
dc.date.submitted2011-08
dc.identifier.issn1433-7851
dc.identifier.issn1521-3773
dc.identifier.urihttp://hdl.handle.net/1721.1/72121
dc.description.abstractShape dependent: Fluorescent quantum-dot-based nanospheres and nanorods with identical hydrodynamic size and surface properties but different aspect ratios were developed for real-time in vivo tumor imaging. The nanorods exhibited superior transport and distribution into mammary tumors in vivo versus nanospheres of similar plasma half-life.en_US
dc.description.sponsorshipNational Cancer Institute (U.S.) (Grant Number R01-CA126642)en_US
dc.description.sponsorshipMIT-Harvard Center for Cancer Nanotechnology Excellence (1U54-CA119349)en_US
dc.description.sponsorshipMassachusetts Institute of Technology. Dept. of Chemistry Instrumentation Facility (CHE-980806)en_US
dc.description.sponsorshipMassachusetts Institute of Technology. Dept. of Chemistry Instrumentation Facility (DBI-9729592)en_US
dc.description.sponsorshipISN (W911NF-07-D-0004)en_US
dc.language.isoen_US
dc.publisherWiley Blackwell (John Wiley & Sons)en_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/anie.201104449en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alike 3.0en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.sourcePMCen_US
dc.titleFluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetrationen_US
dc.typeArticleen_US
dc.identifier.citationChauhan, Vikash P. et al. “Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration.” Angewandte Chemie International Edition 50.48 (2011): 11417–11420.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.approverBawendi, Moungi G.
dc.contributor.mitauthorPopovic, Zoran
dc.contributor.mitauthorChen, Ou
dc.contributor.mitauthorCui, Jian
dc.contributor.mitauthorBawendi, Moungi G.
dc.relation.journalAngewandte Chemie International Editionen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsChauhan, Vikash P.; Popović, Zoran; Chen, Ou; Cui, Jian; Fukumura, Dai; Bawendi, Moungi G.; Jain, Rakesh K.en
dc.identifier.orcidhttps://orcid.org/0000-0003-2220-4365
mit.licenseOPEN_ACCESS_POLICYen_US
mit.metadata.statusComplete


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