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The genetic prehistory of southern Africa

Research and Teaching Output of the MIT Community

Show simple item record Pickrell, Joseph K. Patterson, Nick Barbieri, Chiara Berthold, Falko Gerlach, Linda Güldemann, Tom Kure, Blesswell Mpoloka, Sununguko Wata Nakagawa, Hirosi Naumann, Christfried Lipson, Mark Loh, Po-Ru Lachance, Joseph Mountain, Joanna Bustamante, Carlos D. Berger, Bonnie Tishkoff, Sarah A. Henn, Brenna M. Stoneking, Mark Reich, David Pakendorf, Brigitte 2013-08-16T12:58:31Z 2013-08-16T12:58:31Z 2012-10 2012-08
dc.identifier.issn 2041-1723
dc.description Author manuscript September 17, 2012 en_US
dc.description.abstract Southern and eastern African populations that speak non-Bantu languages with click consonants are known to harbour some of the most ancient genetic lineages in humans, but their relationships are poorly understood. Here, we report data from 23 populations analysed at over half a million single-nucleotide polymorphisms, using a genome-wide array designed for studying human history. The southern African Khoisan fall into two genetic groups, loosely corresponding to the northwestern and southeastern Kalahari, which we show separated within the last 30,000 years. We find that all individuals derive at least a few percent of their genomes from admixture with non-Khoisan populations that began ~1,200 years ago. In addition, the East African Hadza and Sandawe derive a fraction of their ancestry from admixture with a population related to the Khoisan, supporting the hypothesis of an ancient link between southern and eastern Africa. en_US
dc.language.iso en_US
dc.publisher Nature Publishing Group en_US
dc.relation.isversionof en_US
dc.rights Creative Commons Attribution-Noncommercial-Share Alike 3.0 en_US
dc.rights.uri en_US
dc.source arXiv en_US
dc.title The genetic prehistory of southern Africa en_US
dc.type Article en_US
dc.identifier.citation Pickrell, Joseph K., Nick Patterson, Chiara Barbieri, Falko Berthold, Linda Gerlach, Tom Güldemann, Blesswell Kure, et al. “The genetic prehistory of southern Africa.” Nature Communications 3 (October 16, 2012): 1143. en_US
dc.contributor.department Massachusetts Institute of Technology. Department of Mathematics en_US
dc.contributor.department Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory en_US
dc.contributor.mitauthor Lipson, Mark en_US
dc.contributor.mitauthor Loh, Po-Ru en_US
dc.contributor.mitauthor Berger, Bonnie en_US
dc.relation.journal Nature Communications en_US
dc.identifier.mitlicense OPEN_ACCESS_POLICY en_US
dc.eprint.version Author's final manuscript en_US
dc.type.uri en_US
eprint.status en_US
dspace.orderedauthors Pickrell, Joseph K.; Patterson, Nick; Barbieri, Chiara; Berthold, Falko; Gerlach, Linda; Güldemann, Tom; Kure, Blesswell; Mpoloka, Sununguko Wata; Nakagawa, Hirosi; Naumann, Christfried; Lipson, Mark; Loh, Po-Ru; Lachance, Joseph; Mountain, Joanna; Bustamante, Carlos D.; Berger, Bonnie; Tishkoff, Sarah A.; Henn, Brenna M.; Stoneking, Mark; Reich, David; Pakendorf, Brigitte en_US

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