Fabrication of a Hybrid Microfluidic System Incorporating both Lithographically Patterned Microchannels and a 3D Fiber-Formed Microfluidic Network

Author(s)
Bellan, Leon M.; Kniazeva, Tatiana; Kim, Ernest S.; Epshteyn, Alla A.; Cropek, Donald M.; ... Show more
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Abstract
A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With this improved delivery ability comes an increased fluidic resistance due to the tortuous network of small-diameter channels.
Date issued
2012-03
URI
http://hdl.handle.net/1721.1/91502
Department
Charles Stark Draper Laboratory; Massachusetts Institute of Technology. Center for Biomedical Engineering; Koch Institute for Integrative Cancer Research at MIT
Journal
Advanced Healthcare Materials
Publisher
Wiley-VCH Verlag GmbH & Co.
Citation
Bellan, Leon M., Tatiana Kniazeva, Ernest S. Kim, Alla A. Epshteyn, Donald M. Cropek, Robert Langer, and Jeffrey T. Borenstein. “Fabrication of a Hybrid Microfluidic System Incorporating Both Lithographically Patterned Microchannels and a 3D Fiber-Formed Microfluidic Network.” Advanced Healthcare Materials 1, no. 2 (January 20, 2012): 164–167.
Version: Author's final manuscript
ISSN
21922640
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