| dc.contributor.author | Roushdy, O. | |
| dc.contributor.author | Dokov, Rangel P. | |
| dc.contributor.author | Sharei, Armon Reza | |
| dc.contributor.author | Jensen, Klavs F. | |
| dc.contributor.author | Roushdy, O. | |
| dc.contributor.author | Adamo, Andrea, 1975- | |
| dc.date.accessioned | 2014-11-13T19:38:29Z | |
| dc.date.available | 2014-11-13T19:38:29Z | |
| dc.date.issued | 2013-02 | |
| dc.date.submitted | 2013-01 | |
| dc.identifier.issn | 0960-1317 | |
| dc.identifier.issn | 1361-6439 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/91556 | |
| dc.description.abstract | We present a microfluidic-based injection system designed to achieve intracellular delivery of macromolecules by directing a picoliter jet of a solution toward the individual cells. After discussing the concept, we present design specification and criteria, elucidate performance and discuss results. The method has the potential to be quantitative and of high throughput, overcoming the limitations of current intracellular delivery protocols. | en_US |
| dc.description.sponsorship | Deshpande Center for Technological Innovation | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Grant RC1 EB011187-02) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | IOP Publishing | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1088/0960-1317/23/3/035026 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Microfluidic jet injection for delivering macromolecules into cells | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Adamo, A, O Roushdy, R Dokov, A Sharei, and K F Jensen. “Microfluidic Jet Injection for Delivering Macromolecules into Cells.” J. Micromech. Microeng. 23, no. 3 (February 6, 2013): 035026. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemical Engineering | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Mechanical Engineering | en_US |
| dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
| dc.contributor.mitauthor | Adamo, Andrea | en_US |
| dc.contributor.mitauthor | Roushdy, O. | en_US |
| dc.contributor.mitauthor | Dokov, Rangel P. | en_US |
| dc.contributor.mitauthor | Sharei, Armon Reza | en_US |
| dc.contributor.mitauthor | Jensen, Klavs F. | en_US |
| dc.relation.journal | Journal of Micromechanics and Microengineering | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Adamo, A; Roushdy, O; Dokov, R; Sharei, A; Jensen, K F | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0001-7192-580X | |
| dspace.mitauthor.error | true | |
| mit.license | OPEN_ACCESS_POLICY | en_US |
| mit.metadata.status | Complete | |
