Analysis of Short-Term Change in Subfoveal Choroidal Thickness in Eyes With Age-Related Macular Degeneration Using Optical Coherence Tomography
Author(s)Fein, Jordana G.; Branchini, Lauren A.; Manjunath, Varsha; Regatieri, Caio V.; Fujimoto, James G.; Duker, Jay S.; ... Show more Show less
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Background and Objective—To measure the subfoveal choroidal thickness in patients with age-related macular degeneration (AMD) over 6 months. Study Design/Patients and Methods—A retrospective, observational study of patients with AMD followed for 6 months at the New England Eye Center. Baseline and 6 month subfoveal choroidal thickness was measured using spectral domain OCT and compared. Results—For the entire cohort there was statistically significant thinning of the subfoveal choroidal thickness at 6 months compared to baseline, which was driven by the cohort of patients with neovascular AMD [181.2 +/− 75 μm to 173.4 +/− 63 μm] p=0.049. (Figure and Table 1). Conclusions—There was a statistically significant decrease in subfoveal choroidal thickness observed in this cohort of patients with AMD over 6 months, but it was driven by one subgroup, those patients with neovascular age related macular degeneration
DepartmentMassachusetts Institute of Technology. Department of Electrical Engineering and Computer Science; Massachusetts Institute of Technology. Research Laboratory of Electronics
Ophthalmic Surgery, Lasers and Imaging Retina
Fein, Jordana G., Lauren A. Branchini, Varsha Manjunath, Caio V. Regatieri, James G. Fujimoto, and Jay S. Duker. “Analysis of Short-Term Change in Subfoveal Choroidal Thickness in Eyes With Age-Related Macular Degeneration Using Optical Coherence Tomography.” Ophthalmic Surg Lasers Imaging Retina 45, no. 1 (January 1, 2014): 32–37.
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