Design of robust metabolic pathways

Author(s)
Umeton, Renato; Stracquadanio, Giovanni; Sorathiya, Anilkumar; Papini, Alessio; Nicosia, Giuseppe; ... Show more
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Abstract
In this paper we investigate plant photosynthesis and microbial fuel cells. We report the following: 1) we introduce and validate a novel multi-objective optimization algorithm, PMO2; 2) in photosynthesis we increase the yield of 135%, while in Geobacter sulfurreducens we determine the tradeoff for growth versus redox properties; 3) finally, we discuss Pareto-Front as an estimator of robust metabolic pathways.
Date issued
2011-06
URI
http://hdl.handle.net/1721.1/101144
Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
Journal
Proceedings of the 48th Design Automation Conference on (DAC '11)
Publisher
Association for Computing Machinery (ACM)
Citation
Renato Umeton, Giovanni Stracquadanio, Anilkumar Sorathiya, Pietro Liò, Alessio Papini, and Giuseppe Nicosia. 2011. Design of robust metabolic pathways. In Proceedings of the 48th Design Automation Conference (DAC '11). ACM, New York, NY, USA, 747-752.
Version: Author's final manuscript
ISBN
9781450306362
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