MIT Libraries logoDSpace@MIT

MIT
View Item 
  • DSpace@MIT Home
  • MIT Open Access Articles
  • MIT Open Access Articles
  • View Item
  • DSpace@MIT Home
  • MIT Open Access Articles
  • MIT Open Access Articles
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

A Method to Noninvasively Identify Cardiac Bioelectrical Sources

Author(s)
Sohn, Kwanghyun; Lv, Wener; Lee, Kichang; Galea, Anna; Hirschman, Gordon; Barrett, Conor; Cohen, Richard J.; Armoundas, Antonis A.; ... Show more Show less
Thumbnail
DownloadCohen_A method to.pdf (412.6Kb)
OPEN_ACCESS_POLICY

Open Access Policy

Creative Commons Attribution-Noncommercial-Share Alike

Terms of use
Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/
Metadata
Show full item record
Abstract
Background We have introduced a method to guide radiofrequency catheter ablation (RCA) procedures that estimates the location of a catheter tip used to pace the ventricles and the target site for ablation using the single equivalent moving dipole (SEMD). Objective To investigate the accuracy of this method in resolving epicardial and endocardial electrical sources. Methods Two electrode arrays, each of nine pacing electrodes at known distances from each other, sutured on the left- and right-ventricular (LV and RV) epicardial surfaces of swine, were used to pace the heart at multiple rates, while body surface potentials from 64 sites were recorded and used to estimate the SEMD location. A similar approach was followed for pacing from catheters in the LV and RV. Results The overall (RV & LV) error in estimating the interelectrode distance of adjacent epicardial electrodes was 0.38 ± 0.45 cm. The overall endocardial (RV & LV) interelectrode distance error, was 0.44 ± 0.26 cm. Heart rate did not significantly affect the error of the estimated SEMD location (P > 0.05). The guiding process error became progressively smaller as the SEMD approached an epicardial target site and close to the target, the overall absolute error was ∼0.28 cm. The estimated epicardial SEMD locations preserved their topology in image space with respect to their corresponding physical location of the epicardial electrodes. Conclusion The proposed algorithm suggests one can efficiently and accurately resolve epicardial electrical sources without the need of an imaging modality. In addition, the error in resolving these sources is sufficient to guide RCA procedures.
Date issued
2014-03
URI
http://hdl.handle.net/1721.1/102578
Department
Massachusetts Institute of Technology. Institute for Medical Engineering & Science; Harvard University--MIT Division of Health Sciences and Technology
Journal
Pacing and Clinical Electrophysiology
Publisher
Wiley Blackwell
Citation
Sohn, Kwanghyun, Wener Lv, Kichang Lee, Anna Galea, Gordon Hirschman, Conor Barrett, Richard J. Cohen, and Antonis A. Armoundas. “A Method to Noninvasively Identify Cardiac Bioelectrical Sources.” Pacing and Clinical Electrophysiology 37, no. 8 (August 2014): 1038–50.
Version: Author's final manuscript
ISSN
01478389
1540-8159

Collections
  • MIT Open Access Articles

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

Login

Statistics

OA StatisticsStatistics by CountryStatistics by Department
MIT Libraries
PrivacyPermissionsAccessibilityContact us
MIT
Content created by the MIT Libraries, CC BY-NC unless otherwise noted. Notify us about copyright concerns.