| dc.contributor.author | King, Jonathan | en_US |
| dc.coverage.temporal | Fall 2007 | en_US |
| dc.date.issued | 2007-12 | |
| dc.identifier | 7.88J-Fall2007 | |
| dc.identifier | local: 7.88J | |
| dc.identifier | local: 7.24J | |
| dc.identifier | local: 5.48J | |
| dc.identifier | local: 10.543J | |
| dc.identifier | local: IMSCP-MD5-b1f4093c16343d4a95bdb9c82a98d028 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/103817 | |
| dc.description.abstract | This course focuses on the mechanisms by which the amino acid sequence of polypeptide chains (proteins), determine their three-dimensional conformation. Topics in this course include sequence determinants of secondary structure, the folding of newly synthesized polypeptide chains within cells, folding intermediates aggregation and competing off-pathway reactions, and the unfolding and refolding of proteins in vitro. Additional topics covered are the role of helper proteins such as chaperonins and isomerases, protein recovery problems in the biotechnology industry, and diseases found associated with protein folding defects. | en_US |
| dc.language | en-US | en_US |
| dc.relation | | en_US |
| dc.relation | | en_US |
| dc.rights.uri | Usage Restrictions: This site (c) Massachusetts Institute of Technology 2016. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions. | en_US |
| dc.rights.uri | Usage Restrictions: Attribution-NonCommercial-ShareAlike 3.0 Unported | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | en_US |
| dc.subject | 260404 | en_US |
| dc.subject | Developmental Biology and Embryology | en_US |
| dc.title | 7.88J / 7.24J / 5.48J / 10.543J Protein Folding Problem, Fall 2007 | en_US |
| dc.title.alternative | Protein Folding Problem | en_US |
| dc.type | Learning Object | |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemical Engineering | |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | |
