A Central Role for mTOR in Lipid Homeostasis

Author(s)
Lamming, Dudley W.; Sabatini, David M.; Lamming, Dudley W.; Sabatini, David
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Abstract
The mechanistic target of rapamycin (mTOR) signaling pathway regulates many fundamental metabolic and physiological processes, including lipid metabolism. We explore recent findings on the role of mTOR in lipid homeostasis, with an emphasis on recent findings from in vivo models regarding the role of mTORC2 in lipolysis, lipogenesis, and adipogenesis.
Date issued
2013-08
URI
http://hdl.handle.net/1721.1/103878
Department
Massachusetts Institute of Technology. Department of Biology; Whitehead Institute for Biomedical Research; Koch Institute for Integrative Cancer Research at MIT
Journal
Cell Metabolism
Publisher
Elsevier
Citation
Lamming, Dudley W., and David M. Sabatini. “A Central Role for mTOR in Lipid Homeostasis.” Cell Metabolism 18, no. 4 (October 2013): 465-469.
Version: Author's final manuscript
ISSN
15504131
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