Smart nanosystems: Bio-inspired technologies that interact with the host environment

Author(s)
Kwon, Ester; Lo, Justin H.; Bhatia, Sangeeta N
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Abstract
Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the host environment to interact with engineered nanoparticles. Smart nanosystems have the potential to produce personalized diagnostic and therapeutic schema by using the local environment to drive material behavior and ultimately improve human health.
Date issued
2015-11
URI
http://hdl.handle.net/1721.1/103977
Department
Massachusetts Institute of Technology. Institute for Medical Engineering & Science; Koch Institute for Integrative Cancer Research at MIT
Journal
Proceedings of the National Academy of Sciences
Publisher
National Academy of Sciences (U.S.)
Citation
Kwon, Ester J., Justin H. Lo, and Sangeeta N. Bhatia. “Smart Nanosystems: Bio-Inspired Technologies That Interact with the Host Environment.” Proc Natl Acad Sci USA 112, no. 47 (November 23, 2015): 14460–14466. © 2016 National Academy of Sciences.
Version: Final published version
ISSN
0027-8424
1091-6490
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