H5N1 highly pathogenic avian influenza virus isolated from conjunctiva of a whooper swan with neurological signs

Author(s)
Bui, Vuong N.; Ogawa, Haruko; Ngo, Lai H.; Baatartsogt, Tugsbaatar; Abao, Lary N. B.; ... Show more
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Abstract
An H5N1 highly pathogenic avian influenza virus was isolated from conjunctiva of a whooper swan with neurological signs, which was captured during the latest H5N1 HPAI outbreak in Japan. The conjunctival swab contained a larger amount of the virus in comparison with the tracheal swab. This is the first report on H5N1 virus isolation from the conjunctiva of a wild bird, and the result may suggest the conjunctival swab to be a critical sample for H5N1 HPAIV detection in waterfowl. Phylogenetic analysis of the HA gene indicated that the virus falls into H5N1 clade 2.3.2.1.
Date issued
2012-10
URI
http://hdl.handle.net/1721.1/104355
Department
Massachusetts Institute of Technology. Department of Biological Engineering
Journal
Archives of Virology
Publisher
Springer Vienna
Citation
Bui, Vuong N., Haruko Ogawa, Lai H. Ngo, Tugsbaatar Baatartsogt, Lary N. B. Abao, Shio Tamaki, Keisuke Saito, Yukiko Watanabe, Jonathan Runstadler, and Kunitoshi Imai. "H5N1 highly pathogenic avian influenza virus isolated from conjunctiva of a whooper swan with neurological signs." Archives of Virology 158:2 (February 2013), pp. 451-455.
Version: Author's final manuscript
ISSN
0304-8608
1432-8798
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