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Biomarkers and diagnostic tools for detection of Helicobacter pylori

Author(s)
Khalilpour, Akbar; Kazemzadeh-Narbat, Mehdi; Tamayol, Ali; Oklu, Rahmi; Khademhosseini, Alireza
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Abstract
Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms.
Date issued
2016-04
URI
http://hdl.handle.net/1721.1/104361
Department
Institute for Medical Engineering and Science; Harvard University--MIT Division of Health Sciences and Technology
Journal
Applied Microbiology and Biotechnology
Publisher
Springer Berlin Heidelberg
Citation
Khalilpour, Akbar, Mehdi Kazemzadeh-Narbat, Ali Tamayol, Rahmi Oklu, and Ali Khademhosseini. “Biomarkers and Diagnostic Tools for Detection of Helicobacter Pylori.” Applied Microbiology and Biotechnology 100, no. 11 (April 15, 2016): 4723-4734.
Version: Author's final manuscript
ISSN
0175-7598
1432-0614

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