Biomarkers and diagnostic tools for detection of Helicobacter pylori
Author(s)Khalilpour, Akbar; Kazemzadeh-Narbat, Mehdi; Tamayol, Ali; Oklu, Rahmi; Khademhosseini, Alireza
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Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms.
DepartmentInstitute for Medical Engineering and Science; Harvard University--MIT Division of Health Sciences and Technology
Applied Microbiology and Biotechnology
Springer Berlin Heidelberg
Khalilpour, Akbar, Mehdi Kazemzadeh-Narbat, Ali Tamayol, Rahmi Oklu, and Ali Khademhosseini. “Biomarkers and Diagnostic Tools for Detection of Helicobacter Pylori.” Applied Microbiology and Biotechnology 100, no. 11 (April 15, 2016): 4723-4734.
Author's final manuscript