Antiviral and Antibacterial Polyurethanes of Various Modalities
Author(s)Park, Daewon; Wang, Yadong; Larson, Alyssa Maxine; Klibanov, Alexander M
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We have prepared and characterized a new polyurethane-based antimicrobial material, N,N-dodecyl,methyl-polyurethane (Quat-12-PU). It exhibits strong antiviral and antibacterial activities when coated (as an organic solution or an aqueous nanosuspension) onto surfaces and antibacterial activity when electrospun into nanofibers. Quat-12-PU surfaces are able to kill airborne Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli bacteria, as well as inactivate the enveloped influenza virus (but not the non-enveloped poliovirus).
DepartmentMassachusetts Institute of Technology. Department of Biological Engineering; Massachusetts Institute of Technology. Department of Chemistry
Applied Biochemistry and Biotechnology
Park, Daewon, Alyssa M. Larson, Alexander M. Klibanov, and Yadong Wang. “Antiviral and Antibacterial Polyurethanes of Various Modalities.” Applied Biochemistry and Biotechnology 169, no. 4 (January 10, 2013): 1134–1146.
Author's final manuscript