Oscillatory multiphase flow strategy for chemistry and biology
Author(s)
Abolhasani, Milad; Jensen, Klavs F
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Continuous multiphase flow strategies are commonly employed for high-throughput parameter screening of physical, chemical, and biological processes as well as continuous preparation of a wide range of fine chemicals and micro/nano particles with processing times up to 10 min. The inter-dependency of mixing and residence times, and their direct correlation with reactor length have limited the adaptation of multiphase flow strategies for studies of processes with relatively long processing times (0.5–24 h). In this frontier article, we describe an oscillatory multiphase flow strategy to decouple mixing and residence times and enable investigation of longer timescale experiments than typically feasible with conventional continuous multiphase flow approaches. We review current oscillatory multiphase flow technologies, provide an overview of the advancements of this relatively new strategy in chemistry and biology, and close with a perspective on future opportunities.
Date issued
2016-07Department
Massachusetts Institute of Technology. Department of Chemical EngineeringJournal
Lab on a Chip
Publisher
Royal Society of Chemistry
Citation
Abolhasani, Milad, and Klavs F. Jensen. “Oscillatory Multiphase Flow Strategy for Chemistry and Biology.” Lab Chip 16.15 (2016): 2775–2784. © 2016 Royal Society of Chemistry
Version: Final published version
ISSN
1473-0197
1473-0189