A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
Author(s)
Madisen, Linda; Mao, Tianyi; Koch, Henner; Zhuo, Jia-min; Berenyi, Antal; Fujisawa, Shigeyoshi; Hsu, Yun-Wei A; Garcia, Alfredo J; Gu, Xuan; Zanella, Sebastien; Kidney, Jolene; Gu, Hong; Mao, Yimei; Hooks, Bryan M; Buzsáki, György; Ramirez, Jan Marino; Jones, Allan R; Svoboda, Karel; Han, Xue; Turner, Eric E; Zeng, Hongkui; Boyden, Edward; ... Show more Show less
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We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within
some individual crystal grains, but preserves long spin coherence times. Using the native NVs as nanoscale sensors, we introduce a three-dimensional strain imaging technique with high sensitivity (<10[superscript -5] Hz[superscript –1/2]) and diffraction-limited resolution across a wide field of view.
Date issued
2012-03Department
Massachusetts Institute of Technology. Media LaboratoryJournal
Nature Neuroscience
Publisher
Nature Publishing Group
Citation
Madisen, Linda et al. “A Toolbox of Cre-Dependent Optogenetic Transgenic Mice for Light-Induced Activation and Silencing.” Nature Neuroscience 15.5 (2012): 793–802.
Version: Author's final manuscript
ISSN
1097-6256
1546-1726