Building Robust Transcriptomes with Master Splicing Factors
Author(s)Sharp, Phillip A.; Jangi, Mohini Rohit
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Coherent splicing networks arise from many discrete splicing decisions regulated in unison. Here, we examine the properties of robust, context-specific splicing networks. We propose that a subset of key splicing regulators, or “master splicing factors,” respond to environmental cues to establish and maintain tissue transcriptomes during development.
DepartmentDavid H. Koch Institute for Integrative Cancer Research at MIT; Massachusetts Institute of Technology. Department of Biology
Jangi, Mohini, and Phillip A. Sharp. “Building Robust Transcriptomes with Master Splicing Factors.” Cell 159, no. 3 (October 2014): 487–498. © 2014 Elsevier Inc.
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