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Creating Isolated Liquid Compartments Using Photopatterned Obstacles in Microfluidics

Author(s)
Lee, Hyundo; Gupta, Ankur; Hatton, Trevor Alan; Doyle, Patrick S
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Abstract
We propose a method to trap liquid (both oil and water) in a microchannel by sequentially injecting oil and water (or vice versa) over photopatterned obstacles with controlled wetting properties. We present a simple geometrical model to understand the liquid-entrapment process and predict the evolution of the water/oil interface over an obstacle. Our analysis provides an analytic solution that can successfully predict useful properties such as angular position of pinch-off and the amount of captured liquid. We show that we are able to obtain a liquid bridge over two circular obstacles, and we are also able to predict the condition for the formation of a bridge. We further demonstrate the effect of the obstacle shape and how a sudden change in gradient results in larger liquid entrapment. We also demonstrate the ability to entrap isolated liquid chambers for parallel experimentation.
Date issued
2017-04
URI
http://hdl.handle.net/1721.1/109165
Department
Massachusetts Institute of Technology. Department of Chemical Engineering; Massachusetts Institute of Technology. Department of Mechanical Engineering
Journal
Physical Review Applied
Publisher
American Physical Society
Citation
Lee, Hyundo; Gupta, Ankur; Hatton, T. Alan and Doyle, Patrick S. "Creating Isolated Liquid Compartments Using Photopatterned Obstacles in Microfluidics." Physical Review Applied 7, no. 044013 (April 2017): 1-13 © 2017 American Physical Society
Version: Final published version
ISSN
2331-7019

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