Synthetic communities, the sum of parts
Author(s)
Teague, Brian Paul; Weiss, Ron
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Synthetic communities, the sum of parts
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Cooperation between cells is one of evolution's fundamental innovations. It allows cells to specialize: Different members of a consortium assume different responsibilities, increasing overall productivity and allowing for more complex behavior than is possible with a single cell or a monoculture (1). These features of natural systems have attracted the attention of synthetic biologists, who have made engineering of cooperation between cells a long-standing goal. On page 986 of this issue, Chen et al. (2) report the creation of a synthetic consortium of cooperating Escherichia coli bacteria. The design principles they demonstrate have important implications for the construction of multicellular synthetic systems.
Date issued
2015-08Department
Massachusetts Institute of Technology. Department of Biological Engineering; Massachusetts Institute of Technology. Research Laboratory of ElectronicsJournal
Science
Publisher
American Association for the Advancement of Science (AAAS)
Citation
Teague, B. P. and Weiss, R. “Synthetic Communities, the Sum of Parts.” Science 349, no. 6251 (August 2015): 924–925. © 2015 American Association for the Advancement of Science
Version: Original manuscript
ISSN
0036-8075
1095-9203