dc.contributor.author | Guerin, Bastien | |
dc.contributor.author | Akgun, Can | |
dc.contributor.author | Martin, Adrian | |
dc.contributor.author | Torrado-Carvajal, Angel | |
dc.contributor.author | Malpica, Norberto | |
dc.contributor.author | Hernandez-Tamames, Juan A. | |
dc.contributor.author | Schiavi, Emanuele | |
dc.contributor.author | Eryaman, Yigitcan | |
dc.contributor.author | Lopez Herraiz, Joaquin | |
dc.contributor.author | Adalsteinsson, Elfar | |
dc.contributor.author | Wald, Lawrence | |
dc.date.accessioned | 2017-07-17T18:01:20Z | |
dc.date.available | 2017-07-17T18:01:20Z | |
dc.date.issued | 2015-04 | |
dc.date.submitted | 2014-05 | |
dc.identifier.issn | 0740-3194 | |
dc.identifier.issn | 1522-2594 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/110737 | |
dc.description.abstract | Purpose
Specific absorption rate (SAR) amplification around active implantable medical devices during diagnostic MRI procedures poses a potential risk for patient safety. In this study, we present a parallel transmit (pTx) strategy that can be used to safely scan patients with deep brain stimulation (DBS) implants.
Methods
We performed electromagnetic simulations at 3T using a uniform phantom and a multitissue realistic head model with a generic DBS implant. Our strategy is based on using implant-friendly modes, which are defined as the modes of an array that reduce the local SAR around the DBS lead tip. These modes are used in a spokes pulse design algorithm in order to produce highly uniform magnitude least-squares flip angle excitations.
Results
Local SAR (1 g) at the lead tip is reduced below 0.1 W/kg compared with 31.2 W/kg, which is obtained by a simple quadrature birdcage excitation without any sort of SAR mitigation. For the multitissue realistic head model, peak 10 g local SAR and global SAR are obtained as 4.52 W/kg and 0.48 W/kg, respectively. A uniform axial flip angle is also obtained (NRMSE <3%).
Conclusion
Parallel transmit arrays can be used to generate implant-friendly modes and to reduce SAR around DBS implants while constraining peak local SAR and global SAR and maximizing flip angle homogeneity. Magn Reson Med 73:1896–1903, 2015. | en_US |
dc.description.sponsorship | National Institute of Biomedical Imaging and Bioengineering (U.S.) (R01EB006847) | en_US |
dc.description.sponsorship | National Institute of Biomedical Imaging and Bioengineering (U.S.) (R01EB007942) | en_US |
dc.language.iso | en_US | |
dc.publisher | Wiley Blackwell | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1002/mrm.25324 | en_US |
dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
dc.source | PMC | en_US |
dc.title | Parallel transmit pulse design for patients with deep brain stimulation implants | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Eryaman, Yigitcan; Guerin, Bastien; Akgun, Can et al. “Parallel Transmit Pulse Design for Patients with Deep Brain Stimulation Implants.” Magnetic Resonance in Medicine 73, 5 (June 2014): 1896–1903 © 2014 Wiley Periodicals, Inc | en_US |
dc.contributor.department | Institute for Medical Engineering and Science | en_US |
dc.contributor.department | Harvard University--MIT Division of Health Sciences and Technology | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Research Laboratory of Electronics | en_US |
dc.contributor.mitauthor | Eryaman, Yigitcan | |
dc.contributor.mitauthor | Lopez Herraiz, Joaquin | |
dc.contributor.mitauthor | Adalsteinsson, Elfar | |
dc.contributor.mitauthor | Wald, Lawrence | |
dc.relation.journal | Magnetic Resonance in Medicine | en_US |
dc.eprint.version | Author's final manuscript | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dspace.orderedauthors | Eryaman, Yigitcan; Guerin, Bastien; Akgun, Can; Herraiz, Joaquin L.; Martin, Adrian; Torrado-Carvajal, Angel; Malpica, Norberto; Hernandez-Tamames, Juan A.; Schiavi, Emanuele; Adalsteinsson, Elfar; Wald, Lawrence L. | en_US |
dspace.embargo.terms | N | en_US |
dc.identifier.orcid | https://orcid.org/0000-0001-7208-8863 | |
dc.identifier.orcid | https://orcid.org/0000-0002-7637-2914 | |
mit.license | OPEN_ACCESS_POLICY | en_US |