IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy

Author(s)
Cheng, Chia-Wei; Yilmaz, Omer
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IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy
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Abstract
Patients with type 1 diabetes (T1D) often experience gastrointestinal enteropathy (DE) of unclear etiology. Now in Cell Stem Cell, D’Addio et al. (2015) utilize organoid culture models to study the roles of stem cells in DE and show that circulating IGF/IGFBP3 controls colonic stem cell function during homeostasis and in T1D patients.
Date issued
2015-10
URI
http://hdl.handle.net/1721.1/112089
Department
Massachusetts Institute of Technology. Department of Biology; Koch Institute for Integrative Cancer Research at MIT
Journal
Cell Stem Cell
Publisher
Elsevier
Citation
Cheng, Chia-Wei, and Yilmaz, Ömer H. “IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy.” Cell Stem Cell 17, 4 (October 2015): 379–380 © 2015 Elsevier Inc
Version: Original manuscript
ISSN
1934-5909
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