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Neurobiology of rodent self-grooming and its value for translational neuroscience

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dc.contributor.author Kalueff, Allan V.
dc.contributor.author Stewart, Adam Michael
dc.contributor.author Song, Cai
dc.contributor.author Berridge, Kent C.
dc.contributor.author Fentress, John C.
dc.contributor.author Graybiel, Ann M
dc.date.accessioned 2017-11-14T16:49:33Z
dc.date.available 2017-11-14T16:49:33Z
dc.date.issued 2017-11-14
dc.identifier.issn 1471-003X
dc.identifier.issn 1471-0048
dc.identifier.uri http://hdl.handle.net/1721.1/112180
dc.description.abstract Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing pattern and is one of the most frequently performed behavioural activities in rodents. In this Review, we discuss the neurobiology of rodent self-grooming, and we highlight studies of rodent models of neuropsychiatric disorders-including models of autism spectrum disorder and obsessive compulsive disorder-that have assessed self-grooming phenotypes. We suggest that rodent self-grooming may be a useful measure of repetitive behaviour in such models, and therefore of value to translational psychiatry. Assessment of rodent self-grooming may also be useful for understanding the neural circuits that are involved in complex sequential patterns of action. en_US
dc.description.sponsorship National Institutes of Health (U.S.) (Grant NS025529) en_US
dc.description.sponsorship National Institutes of Health (U.S.) (Grant HD028341) en_US
dc.description.sponsorship National Institutes of Health (U.S.) (Grant MH060379) en_US
dc.publisher Nature Publishing Group en_US
dc.relation.isversionof http://dx.doi.org/10.1038/NRN.2015.8 en_US
dc.rights Creative Commons Attribution-Noncommercial-Share Alike en_US
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/ en_US
dc.source PMC en_US
dc.title Neurobiology of rodent self-grooming and its value for translational neuroscience en_US
dc.type Article en_US
dc.identifier.citation Kalueff, Allan V. “Neurobiology of Rodent Self-Grooming and Its Value for Translational Neuroscience.” Nature Reviews Neuroscience 17, 1 (December 2015): 45–59 © 2016 Macmillan Publishers Limited en_US
dc.contributor.department McGovern Institute for Brain Research at MIT en_US
dc.contributor.department Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences en_US
dc.contributor.mitauthor Graybiel, Ann M
dc.relation.journal Nature Reviews Neuroscience en_US
dc.identifier.mitlicense OPEN_ACCESS_POLICY en_US
dc.eprint.version Author's final manuscript en_US
dc.type.uri http://purl.org/eprint/type/JournalArticle en_US
eprint.status http://purl.org/eprint/status/PeerReviewed en_US
dc.date.updated 2017-11-09T16:53:06Z
dspace.orderedauthors Kalueff, Allan V.; Stewart, Adam Michael; Song, Cai; Berridge, Kent C.; Graybiel, Ann M.; Fentress, John C. en_US
dspace.embargo.terms N en_US
dc.identifier.orcid https://orcid.org/0000-0002-4326-7720


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