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Neurobiology of social behavior abnormalities in autism and Williams syndrome

Author(s)
Barak, Boaz; Feng, Guoping
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Abstract
Social behavior is a basic behavior mediated by multiple brain regions and neural circuits, and is crucial for the survival and development of animals and humans. Two neuropsychiatric disorders that have prominent social behavior abnormalities are autism spectrum disorders (ASD), which is characterized mainly by hyposociability, and Williams syndrome (WS), whose subjects exhibit hypersociability. Here we review the unique properties of social behavior in ASD and WS, and discuss the major theories in social behavior in the context of these disorders. We conclude with a discussion of the research questions needing further exploration to enhance our understanding of social behavior abnormalities.
Date issued
2016-04
URI
http://hdl.handle.net/1721.1/112211
Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences; McGovern Institute for Brain Research at MIT
Journal
Nature Neuroscience
Publisher
Nature Publishing Group
Citation
Barak, Boaz, and Feng, Guoping. “Neurobiology of Social Behavior Abnormalities in Autism and Williams Syndrome.” Nature Neuroscience 19, 6 (April 2016): 647–655 © 2016 Nature America, Inc
Version: Author's final manuscript
ISSN
1097-6256
1546-1726

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