Advanced Search
DSpace@MIT

Early Onset of Kinetic Roughening due to a Finite Step Width in Hematin Crystallization

Research and Teaching Output of the MIT Community

Show simple item record

dc.contributor.author Rimer, Jeffrey D.
dc.contributor.author Vekilov, Peter G.
dc.contributor.author Olafson, Katy
dc.date.accessioned 2017-12-06T18:22:22Z
dc.date.available 2017-12-06T18:22:22Z
dc.date.issued 2017-11
dc.date.submitted 2017-03
dc.identifier.issn 0031-9007
dc.identifier.issn 1079-7114
dc.identifier.uri http://hdl.handle.net/1721.1/112615
dc.description.abstract The structure of the interface of a growing crystal with its nutrient phase largely determines the growth dynamics. We demonstrate that hematin crystals, crucial for the survival of malaria parasites, transition from faceted to rough growth interfaces at increasing thermodynamic supersaturation Δμ. Contrary to theoretical predictions and previous observations, this transition occurs at moderate values of Δμ. Moreover, surface roughness varies nonmonotonically with Δμ, and the rate constant for rough growth is slower than that resulting from nucleation and spreading of layers. We attribute these unexpected behaviors to the dynamics of step growth dominated by surface diffusion and the loss of identity of nuclei separated by less than the step width w. We put forth a general criterion for the onset of kinetic roughening using w as a critical length scale. en_US
dc.description.sponsorship National Institutes of Health (U.S.) (Grant 1R21AI126215-01) en_US
dc.description.sponsorship National Science Foundation (U.S.) (Grant DMR-1710354) en_US
dc.description.sponsorship United States. National Aeronautics and Space Administration (Grant NNX14AD68G) en_US
dc.description.sponsorship United States. National Aeronautics and Space Administration (Grant NNX14AE79G) en_US
dc.description.sponsorship Robert A. Welch Foundation (Grant E-1794) en_US
dc.publisher American Physical Society en_US
dc.relation.isversionof http://dx.doi.org/10.1103/PhysRevLett.119.198101 en_US
dc.rights Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. en_US
dc.source American Physical Society en_US
dc.title Early Onset of Kinetic Roughening due to a Finite Step Width in Hematin Crystallization en_US
dc.type Article en_US
dc.identifier.citation Olafson, Katy N. et al. "Early Onset of Kinetic Roughening due to a Finite Step Width in Hematin Crystallization." Physical Review Letters 119, 19 (November 2017): 198101 © 2017 American Physical Society en_US
dc.contributor.department David H. Koch Institute for Integrative Cancer Research at MIT en_US
dc.contributor.department Massachusetts Institute of Technology. Department of Chemical Engineering en_US
dc.contributor.mitauthor Olafson, Katy
dc.relation.journal Physical Review Letters en_US
dc.identifier.mitlicense PUBLISHER_POLICY en_US
dc.eprint.version Final published version en_US
dc.type.uri http://purl.org/eprint/type/JournalArticle en_US
eprint.status http://purl.org/eprint/status/PeerReviewed en_US
dc.date.updated 2017-11-14T22:43:21Z
dc.language.rfc3066 en
dc.rights.holder American Physical Society
dspace.orderedauthors Olafson, Katy N.; Rimer, Jeffrey D.; Vekilov, Peter G. en_US
dspace.embargo.terms N en_US


Files in this item

Name Size Format
Downloadable Full Text - PDF

This item appears in the following Collection(s)

Show simple item record

Open Access