dbOTU3: A new implementation of distribution-based OTU calling

Author(s)
Olesen, Scott Wilder; Duvallet, Claire; Alm, Eric J
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Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0
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Abstract
Distribution-based operational taxonomic unit-calling (dbOTU) improves on other approaches by incorporating information about the input sequences' distribution across samples. Previous implementations of dbOTU presented challenges for users. Here we introduce and evaluate a new implementation of dbOTU that is faster and more user-friendly. We show that this new implementation has theoretical and practical improvements over previous implementations of dbOTU, making the algorithm more accessible to microbial ecology and biomedical researchers.
Date issued
2017-05
URI
http://hdl.handle.net/1721.1/113280
Department
Institute for Medical Engineering and Science; Massachusetts Institute of Technology. Department of Biological Engineering
Journal
PLOS ONE
Publisher
Public Library of Science
Citation
Olesen, Scott W. et al. “dbOTU3: A New Implementation of Distribution-Based OTU Calling.” Edited by Jonathan H. Badger. PLOS ONE 12, 5 (May 2017): e0176335 © 2017 Olesen et al
Version: Original manuscript
ISSN
1932-6203
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