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Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens

Author(s)
Husvogt, Lennart; Vardeh, Hilde; Sheykin, Yury; Faulkner-Jones, Beverly E.; Hornegger, Joachim; Brooker, Jeff; Cable, Alex; Connolly, James L.; Giacomelli, Michael; Yoshitake, Tadayuki; Cahill, Lucas Christopher; Ahsen, Osman Oguz; Fujimoto, James G; ... Show more Show less
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.

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Abstract
We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtual H&E images for real-time assessment. The imaging system and virtual H&E rendering algorithm are demonstrated by imaging unfixed human breast tissue in a clinical setting. Keywords: multiphoton, histology, surgical pathology, H&E
Date issued
2016-03
URI
http://hdl.handle.net/1721.1/115408
Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science; Massachusetts Institute of Technology. Research Laboratory of Electronics
Journal
Proceedings Volume 9712, Multiphoton Microscopy in the Biomedical Sciences XVI
Publisher
SPIE
Citation
Giacomelli, Michael G. et al. “Design of a Portable Wide Field of View GPU-Accelerated Multiphoton Imaging System for Real-Time Imaging of Breast Surgical Specimens.” Proceedings Volume 9712, Multiphoton Microscopy in the Biomedical Sciences XVI, 13-18 February, 2016, San Francisco, California, SPIE, 2016.
Version: Final published version
ISSN
0277-786X
1996-756X

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