Metabolic Teamwork in the Stem Cell Niche

Author(s)
Roper, Jatin; Yilmaz, Omer
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Abstract
Nearby cells can support stem cell differentiation, but the metabolic activities in stem cell niches are unknown. A recent study (Rodríguez-Colman et al., 2017) reveals a metabolic partnership in the intestinal stem cell niche: glycolysis in niche Paneth cells provides lactate to drive mitochondrial oxidative phosphorylation in intestinal stem cells.
Date issued
2017-05
URI
http://hdl.handle.net/1721.1/117191
Department
Massachusetts Institute of Technology. Department of Biology; Koch Institute for Integrative Cancer Research at MIT
Journal
Cell Metabolism
Publisher
Elsevier BV
Citation
Roper, Jatin, and Ömer H. Yilmaz. “Metabolic Teamwork in the Stem Cell Niche.” Cell Metabolism 25, no. 5 (May 2017): 993–994.
Version: Author's final manuscript
ISSN
15504131
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