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Engineering Engineering Hyperthermostable rcSso7d as Reporter Molecule for in Vitro Diagnostic Tests
| dc.contributor.author | Sung, Ki-Joo | |
| dc.contributor.author | Miller, Eric Alexander | |
| dc.contributor.author | Sikes Johnson, Hadley | |
| dc.date.accessioned | 2018-11-19T19:35:53Z | |
| dc.date.available | 2018-11-19T19:35:53Z | |
| dc.date.issued | 2018-10 | |
| dc.date.submitted | 2018-07 | |
| dc.identifier.issn | 2058-9689 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/119208 | |
| dc.description.abstract | The hyperthermostable binding scaffold, rcSso7d, has recently been studied for use in in vitro diagnostic tests but has not yet been demonstrated as a soluble reporter protein. Here, we investigated several rcSso7d protein constructs and biotin conjugation methods to link a detectable signal to the presence of a target biomarker. | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (Grant 1122374) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Royal Society of Chemistry (RSC) | en_US |
| dc.relation.isversionof | http://dx.doi.org/ 10.1039/C8ME00049B | en_US |
| dc.rights | Creative Commons Attribution-NonCommercial 3.0 Unported | en_US |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc/3.0/ | en_US |
| dc.source | Royal Society of Chemistry | en_US |
| dc.title | Engineering Engineering Hyperthermostable rcSso7d as Reporter Molecule for in Vitro Diagnostic Tests | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Sung, Ki-Joo et al. “Engineering Hyperthermostable rcSso7d as Reporter Molecule for in Vitro Diagnostic Tests.” Molecular Systems Design & Engineering 2018, 5 (October 2018) © 2018 Royal Society of Chemistry | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemical Engineering | en_US |
| dc.contributor.mitauthor | Sung, Ki-Joo | |
| dc.contributor.mitauthor | Miller, Eric Alexander | |
| dc.contributor.mitauthor | Sikes Johnson, Hadley | |
| dc.relation.journal | Molecular Systems Design & Engineering | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Sung, Ki-Joo; Miller, Eric A.; Sikes, Hadley D. | en_US |
| dspace.embargo.terms | N | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0001-8120-538X | |
| dc.identifier.orcid | https://orcid.org/0000-0002-6217-3922 | |
| dc.identifier.orcid | https://orcid.org/0000-0002-7096-138X | |
| mit.license | PUBLISHER_CC | en_US |
