Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation
Author(s)Aizenberg, Joanna; Analoui, Mostafa; Andrews, Anne M.; Mooney, David J.; Oklu, Rahmi; Peer, Dan; Stolzoff, Michelle; Webster, Thomas J.; Weiss, Paul S.; Alvarez, Mario Moises; Bisker Raviv, Gili Hana; Boyden, Edward; Kamm, Roger Dale; Karp, Jeffrey; Strano, Michael S.; Trujillo de Santiago, Grissel; Khademhosseini, Alireza; ... Show more Show less
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We discuss the state of the art and innovative micro- and nanoscale technologies that are finding niches and opening up new opportunities in medicine, particularly in diagnostic and therapeutic applications. We take the design of point-of-care applications and the capture of circulating tumor cells as illustrative examples of the integration of micro- and nanotechnologies into solutions of diagnostic challenges. We describe several novel nanotechnologies that enable imaging cellular structures and molecular events. In therapeutics, we describe the utilization of micro- and nanotechnologies in applications including drug delivery, tissue engineering, and pharmaceutical development/testing. In addition, we discuss relevant challenges that micro- and nanotechnologies face in achieving cost-effective and widespread clinical implementation as well as forecasted applications of micro- and nanotechnologies in medicine.
DepartmentHarvard University--MIT Division of Health Sciences and Technology; Massachusetts Institute of Technology. Department of Biological Engineering; Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences; Massachusetts Institute of Technology. Department of Chemical Engineering; Massachusetts Institute of Technology. Department of Mechanical Engineering; Massachusetts Institute of Technology. Media Laboratory; Massachusetts Institute of Technology. Microsystems Technology Laboratories; McGovern Institute for Brain Research at MIT
American Chemical Society (ACS)
Alvarez, Mario M. et al. “Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation.” ACS Nano 11, 6 (May 2017): 5195–5214 © 2017 American Chemical Society
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