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dc.contributor.authorZurovcik, Danielle R.
dc.contributor.authorMody, Gita N.
dc.contributor.authorRiviello, Robert
dc.contributor.authorSlocum, Alexander H
dc.date.accessioned2019-01-24T21:27:15Z
dc.date.available2019-01-24T21:27:15Z
dc.date.issued2015-10
dc.identifier.issn0890-5339
dc.identifier.urihttp://hdl.handle.net/1721.1/120130
dc.description.abstractNegative pressure wound therapy (NPWT) provides proven wound healing benefits and is often a desirable wound treatment methodology. Unfortunately, NPWT devices are not widely available in low-resource settings. To overcome the identified NPWT barriers, a simplified NPWT (sNPWT) system was designed and iteratively improved during field-based testing. The sNPWT technology, our device design iterations, and the design-based results of our field tests are described in this article. The sNPWT system includes a bellows hand pump, an occlusive drape, and a tube with tube connectors, connecting the drape to the pump. The most critical property of an sNPWT system is that it must be airtight. The details of the design iterations, which are needed to achieve an occlusive system, are explained. During the design process, the sNPWT system was tested during the earthquake relief in Haiti. This testing found that a liquid sealant was necessary to seal the drape to the periwound skin. A study conducted in Rwanda verified that a liquid latex sealant was safe to use, and that the tube connector must be connected to the drape with an airtight method during the manufacturing process. This work has shown that sNPWT is feasible in low-resource settings. Since the completion of the clinical testing, the design has been further evolved, and the developers are working with contract manufacturers to produce the final design and preparing for regulatory approval applications.en_US
dc.description.sponsorshipLegatum Center for Development & Entrepreneurship (Massachusetts Institute of Technology)en_US
dc.description.sponsorshipMassachusetts Institute of Technology (Hugh Hampton Young Memorial Fund Fellowship)en_US
dc.description.sponsorshipFogarty International Center (Clinical Research Fellowship)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Fogarty International Center. R24 TW007988)en_US
dc.publisherOvid Technologies (Wolters Kluwer Health)en_US
dc.relation.isversionofhttp://dx.doi.org/10.1097/BOT.0000000000000410en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourcePMCen_US
dc.titleSimplified Negative Pressure Wound Therapy Device for Application in Low-Resource Settingsen_US
dc.typeArticleen_US
dc.identifier.citationZurovcik, Danielle R., Gita N. Mody, Robert Riviello, and Alex Slocum. “Simplified Negative Pressure Wound Therapy Device for Application in Low-Resource Settings.” Journal of Orthopaedic Trauma 29 (October 2015): S33–S36.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Mechanical Engineering
dc.contributor.mitauthorSlocum, Alexander H
dc.relation.journalJournal of Orthopaedic Traumaen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2019-01-02T18:25:43Z
dspace.orderedauthorsZurovcik, Danielle R.; Mody, Gita N.; Riviello, Robert; Slocum, Alexen_US
dspace.embargo.termsNen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-5048-4109
mit.licenseOPEN_ACCESS_POLICYen_US


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