HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease
Author(s)Vunjak-Novakovic, Gordana V; Bhatia, Sangeeta N; Chen, Christopher; Hirschi, Karen
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Our project team is developing an integrated microphysiological platform with functionally connected vascular, liver and cardiac microtissues derived from a single line of human pluripotent stem cells. The platform enables functional representation of human physiology in conjunction with real-time biological readouts (via imaging and homologous reporters for all three cell phenotypes) and compatibility with high-throughput/high-content analysis. In this paper, we summarize progress made over the first year of the grant. Keywords: Vioxx, Glycol Diacrylate, Genotype Pool, Tissue Module, Polyethylene Glycol Diacrylate
DepartmentHarvard University--MIT Division of Health Sciences and Technology
Stem Cell Research & Therapy
Biomed Central Ltd.
Vunjak-Novakovic, Gordana, et al. “HeLiVa Platform: Integrated Heart-Liver-Vascular Systems for Drug Testing in Human Health and Disease.” Stem Cell Research & Therapy, vol. 4, no. Suppl 1, 2013, p. S8. © 2010 BioMed Central Ltd.
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