Synthetic biology devices as tools for metabolic engineering
Author(s)Shiue, Eric; Prather, Kristala L
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Metabolic engineering focuses on controlling cellular metabolism and heterologous pathway flux to maximize the production of a product of interest. In recent years, various " devices" have begun to emerge from synthetic biology which could find widespread application in the field of metabolic engineering. In this review, we describe devices from synthetic biology and discuss the difficulties that may be encountered when using these devices as tools for metabolic engineering. Keywords: Synthetic biology devices; Metabolic engineering; Process integration; Large scale cultivation; Sensors; Scale-up
DepartmentMassachusetts Institute of Technology. Department of Chemical Engineering
Biochemical Engineering Journal
Shiue, Eric and Kristala L. J. Prather. "Synthetic biology devices as tools for metabolic engineering." Biochemical Engineering Journal 65 (June 2012): 82-89 © 2012 Elsevier B.V.
Author's final manuscript