The Tectorial Membrane: Mechanical Properties and Functions

Author(s)
Sellon, Jonathan Blake; Ghaffari, Roozbeh; Freeman, Dennis M
Thumbnail
DownloadThe_tectorial_membrane_Mechanical_properties_and_functions.pdf (2.970Mb)
Terms of use
Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/
Metadata
Show full item record
Abstract
The tectorial membrane (TM) is widely believed to play a critical role in determining the remarkable sensitivity and frequency selectivity that are hallmarks of mammalian hearing. Recently developed mouse models of human hearing disorders have provided new insights into the molecular, nanomechanical mechanisms that underlie resonance and traveling wave properties of the TM. Herein we review recent experimental and theoretical results detailing TM morphology, local poroelastic and electromechanical interactions, and global spread of excitation via TM traveling waves, with direct implications for cochlear mechanisms.
Date issued
2018-10
URI
https://hdl.handle.net/1721.1/122653
Department
Massachusetts Institute of Technology. Research Laboratory of Electronics; Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Journal
Cold Spring Harbor Perspectives in Medicine
Publisher
Cold Spring Harbor Laboratory
Citation
Sellon, Jonathan et al. "The Tectorial Membrane: Mechanical Properties and Functions." Cold Spring Harbor Perspectives in Medicine Cold Spring Harbor 9 (October 2019): a033514 © 2019 Cold Spring Harbor Laboratory Press
Version: Author's final manuscript
ISSN
2157-1422
Collections