dc.contributor.author | Wang, Chen | |
dc.contributor.author | Zhao, Xiao-Ping | |
dc.contributor.author | Liu, Fei-Fei | |
dc.contributor.author | Chen, Yuming | |
dc.contributor.author | Xia, Xing-Hua | |
dc.contributor.author | Li, Ju | |
dc.date.accessioned | 2020-04-06T18:57:20Z | |
dc.date.available | 2020-04-06T18:57:20Z | |
dc.date.issued | 2020-02 | |
dc.date.submitted | 2019-12 | |
dc.identifier.issn | 1530-6992 | |
dc.identifier.issn | 1530-6984 | |
dc.identifier.uri | https://hdl.handle.net/1721.1/124494 | |
dc.description.abstract | Ion transport in an artificial asymmetric nanoporous membrane, which is similar to biological ion channels, can be used for biosensing. Here, a dendrimer-Au nanoparticle network (DAN) is in situ assembled on a nanoporous anodic aluminum oxide (AAO) surface, forming a DAN/AAO hybrid membrane. Benefiting from the high surface area and anion selectivity of DAN, the prepared DAN/AAO hybrid presents selective ion transport. Under a bias potential, a diode-like current-potential (I-V) response is observed. The obtained ionic current rectification (ICR) property can be tuned by the ion valence and pH value of the electrolyte. The rectified ionic current endows the as-prepared DAN/AAO hybrid with the ability of enhanced bioanalysis. Sensitive capture and detection of circulating tumor cells (CTCs) with a detection limit of 80 cells mL-1 as well as excellent reusability can be achieved. ©2020 keywords: dendrimer-Au nanoparticle network; hybrid membrane; ion selectivity; ionic current rectification; enhanced bioanalysis | en_US |
dc.description.sponsorship | National Natural Science Foundation of China (no. 21874155) | en_US |
dc.description.sponsorship | National Natural Science Foundation of China (no. 21635004) | en_US |
dc.description.sponsorship | National Natural Science Foundation of China (no. 21575163) | en_US |
dc.description.sponsorship | Natural Science Foundation of Jiangsu Province (no. BK20191316) | en_US |
dc.description.sponsorship | Double First-Class University project (no. CPU2018GY25) | en_US |
dc.language.iso | en | |
dc.publisher | American Chemical Society (ACS) | en_US |
dc.relation.isversionof | 10.1021/acs.nanolett.9b05066 | en_US |
dc.rights | Creative Commons Attribution 4.0 International license | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_US |
dc.source | ACS | en_US |
dc.title | Dendrimer-Au nanoparticle network covered alumina membrane for ion rectification and enhanced bioanalysis | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Wang, Chen, et al., "Dendrimer-Au nanoparticle network covered alumina membrane for ion rectification and enhanced bioanalysis." Nano letters 20, 3 (2020): p. 1846-54 doi 10.1021/acs.nanolett.9b05066 ©2020 Author(s) | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Materials Science and Engineering | en_US |
dc.relation.journal | Nano letters | en_US |
dc.eprint.version | Final published version | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dc.date.updated | 2020-04-06T14:55:43Z | |
dspace.date.submission | 2020-04-06T14:55:48Z | |
mit.journal.volume | 20 | en_US |
mit.journal.issue | 3 | en_US |
mit.license | PUBLISHER_CC | |
mit.metadata.status | Complete | |