Neurons regulate synaptic strength through homeostatic scaling of active zones
Author(s)
Cunningham, Karen L; Littleton, J. Troy
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How neurons stabilize their overall synaptic strength following conditions that alter synaptic morphology or function is a key question in neuronal homeostasis. In this issue, Goel et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201807165) find that neurons stabilize synaptic output despite disruptions in synapse size, active zone number, or postsynaptic function by controlling the delivery of active zone material and active zone size.
Date issued
2019-05Department
Massachusetts Institute of Technology. Department of Biology; Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences; Picower Institute for Learning and MemoryJournal
The Journal of cell biology
Publisher
Rockefeller University Press
Citation
Cunningham, Karen L. and J. Troy Littleton. “Neurons regulate synaptic strength through homeostatic scaling of active zones.” The Journal of cell biology 218 (2019): 1434-1435 © 2019 The Author(s)
Version: Final published version
ISSN
0021-9525