| dc.contributor.author | Bi, Xiaobao | |
| dc.contributor.author | Yin, Juan | |
| dc.contributor.author | Rao, Chang | |
| dc.contributor.author | Balamkundu, Seetharamsing | |
| dc.contributor.author | Zhang, Dingpeng | |
| dc.contributor.author | Dedon, Peter C | |
| dc.contributor.author | Liu, Chuan-Fa | |
| dc.date.accessioned | 2020-06-19T21:12:56Z | |
| dc.date.available | 2020-06-19T21:12:56Z | |
| dc.date.issued | 2018-12 | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/125905 | |
| dc.description.abstract | A previously undescribed reaction involving the formation of a thiazolidin-5-imine linkage was developed for bio-conjugation. Being highly specific and operating in aqueous media, this simple condensation reaction is used to chemoselectively label peptides, proteins and living cells under physiological conditions without the need to use toxic catalysts or reducing reagents. | en_US |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | https://doi.org/10.1021/acs.orglett.8b03195 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
| dc.source | Josephina Lee | en_US |
| dc.title | Thiazolidin-5-imine Formation as a Catalyst-Free Bioorthogonal Reaction for Protein and Live Cell Labeling | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Bi, Xiaobao et al. "Thiazolidin-5-imine Formation as a Catalyst-Free Bioorthogonal Reaction for Protein and Live Cell Labeling." Organic Letter 20, 24 (December 2018): 7790–7793 © 2018 American Chemical Society | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biological Engineering | en_US |
| dc.contributor.department | Singapore-MIT Alliance in Research and Technology (SMART) | en_US |
| dc.contributor.department | Singapore-MIT Alliance in Research and Technology (SMART) | en_US |
| dc.relation.journal | Organic Letters | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.identifier.doi | 10.1021/acs.orglett.8b03195 | |
| dspace.date.submission | 2020-06-17T22:50:09Z | |
| mit.journal.volume | 20 | en_US |
| mit.journal.issue | 24 | en_US |
| mit.license | PUBLISHER_CC | |
| mit.metadata.status | Complete | |
