Advances in Biomaterials for Drug Delivery
Author(s)Fenton, Owen Shea; Olafson, Katy; Pillai, Padmini S; Mitchell, Michael J.; Langer, Robert S
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Advances in biomaterials for drug delivery are enabling significant progress in biology and medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists, and clinicians generate innovative strategies and materials to treat a range of diseases. Specifically, recent advances include major breakthroughs in materials for cancer immunotherapy, autoimmune diseases, and genome editing. Here, strategies for the design and implementation of biomaterials for drug delivery are reviewed. A brief history of the biomaterials field is first established, and then commentary on RNA delivery, responsive materials development, and immunomodulation are provided. Current challenges associated with these areas as well as opportunities to address long-standing problems in biology and medicine are discussed throughout.
DepartmentDavid H. Koch Institute for Integrative Cancer Research at MIT; Massachusetts Institute of Technology. Department of Chemical Engineering; Harvard University--MIT Division of Health Sciences and Technology
Fenton, Owen S. et al. "Advances in Biomaterials for Drug Delivery." Advance Materials 30, 29 (May 2018): 1705328 © 2018 WILEY-VCH Verlag GmbH & Co
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