Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
Author(s)Rowlands, Christopher J.; Bruns, Oliver T.; Franke, Daniel; Fukamura, Dai; Jain, Rakesh K.; Bawendi, Moungi G.; So, Peter T.C.; ... Show more Show less
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© 2019 IOP Publishing Ltd. The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 μm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue, and demonstrates the value of these optimized wavelengths for neurobiological applications.
DepartmentMassachusetts Institute of Technology. Department of Chemistry
Journal of Physics D: Applied Physics
Rowlands, Christopher J. et al. "Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications." Journal of Physics D: Applied Physics 52, 26 (Apr. 2019): doi 10.1088/1361-6463/AB16B4 ©2019 Author(s)
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