Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications

Author(s)
Rowlands, Christopher J.; Bruns, Oliver T.; Franke, Daniel; Fukamura, Dai; Jain, Rakesh K.; ... Show more
Thumbnail
DownloadPublished version (3.697Mb)
Terms of use
Creative Commons Attribution 3.0 unported license https://creativecommons.org/licenses/by/3.0/
Metadata
Show full item record
Abstract
© 2019 IOP Publishing Ltd. The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 μm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue, and demonstrates the value of these optimized wavelengths for neurobiological applications.
Date issued
2019-04
URI
https://hdl.handle.net/1721.1/126241
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Journal of Physics D: Applied Physics
Publisher
IOP Publishing
Citation
Rowlands, Christopher J. et al. "Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications." Journal of Physics D: Applied Physics 52, 26 (Apr. 2019): doi 10.1088/1361-6463/AB16B4 ©2019 Author(s)
Version: Final published version
ISSN
1361-6463
Collections