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Correction propagation for user-assisted optical coherence tomography segmentation: general framework and application to Bruch’s membrane segmentation

Author(s)
Stromer, Daniel Johann; Moult, Eric Michael; Chen, Siyu; Fujimoto, James G
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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Abstract
Optical coherence tomography (OCT) is a commonly used ophthalmic imaging modality. While OCT has traditionally been viewed cross-sectionally (i.e., as a sequence of B-scans), higher A-scan rates have increased interest in en face OCT visualization and analysis. The recent clinical introduction of OCT angiography (OCTA) has further spurred this interest, with chorioretinal OCTA being predominantly displayed via en face projections. Although en face visualization and quantitation are natural for many retinal features (e.g., drusen and vasculature), it requires segmentation. Because manual segmentation of volumetric OCT data is prohibitively laborious in many settings, there has been significant research and commercial interest in developing automatic segmentation algorithms. While these algorithms have achieved impressive results, the variability of image qualities and the variety of ocular pathologies cause even the most robust automatic segmentation algorithms to err. In this study, we develop a user-assisted segmentation approach, complementary to fully-automatic methods, wherein correction propagation is used to reduce the burden of manually correcting automatic segmentations. The approach is evaluated for Bruch’s membrane segmentation in eyes with advanced age-related macular degeneration.
Date issued
2020-05
URI
https://hdl.handle.net/1721.1/129580
Department
Massachusetts Institute of Technology. Research Laboratory of Electronics; Massachusetts Institute of Technology. Institute for Medical Engineering & Science; Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Journal
Biomedical Optics Express
Publisher
The Optical Society
Citation
Stromer, Daniel et al. “Correction propagation for user-assisted optical coherence tomography segmentation: general framework and application to Bruch’s membrane segmentation.” Biomedical Optics Express, 11, 5 (May 2020): 392759 © 2020 The Author(s)
Version: Final published version
ISSN
2156-7085

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