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dc.contributor.authorKuo, Po-Chih
dc.contributor.authorPollard, Tom Joseph
dc.contributor.authorJohnson, Alistair Edward William
dc.contributor.authorCeli, Leo Anthony G.
dc.date.accessioned2021-04-27T15:28:05Z
dc.date.available2021-04-27T15:28:05Z
dc.date.issued2021-02
dc.date.submitted2020-07
dc.identifier.issn2398-6352
dc.identifier.urihttps://hdl.handle.net/1721.1/130526
dc.description.abstractImage-based teleconsultation using smartphones has become increasingly popular. In parallel, deep learning algorithms have been developed to detect radiological findings in chest X-rays (CXRs). However, the feasibility of using smartphones to automate this process has yet to be evaluated. This study developed a recalibration method to build deep learning models to detect radiological findings on CXR photographs. Two publicly available databases (MIMIC-CXR and CheXpert) were used to build the models, and four derivative datasets containing 6453 CXR photographs were collected to evaluate model performance. After recalibration, the model achieved areas under the receiver operating characteristic curve of 0.80 (95% confidence interval: 0.78–0.82), 0.88 (0.86–0.90), 0.81 (0.79–0.84), 0.79 (0.77–0.81), 0.84 (0.80–0.88), and 0.90 (0.88–0.92), respectively, for detecting cardiomegaly, edema, consolidation, atelectasis, pneumothorax, and pleural effusion. The recalibration strategy, respectively, recovered 84.9%, 83.5%, 53.2%, 57.8%, 69.9%, and 83.0% of performance losses of the uncalibrated model. We conclude that the recalibration method can transfer models from digital CXRs to CXR photographs, which is expected to help physicians’ clinical works.en_US
dc.description.sponsorshipTaiwan. Ministry of Science and Technology (Grant MOST109-2222-E-007-004-MY3)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (R01 grant EB017205)en_US
dc.language.isoen
dc.publisherNature Publishing Groupen_US
dc.relation.isversionof10.1038/s41746-021-00393-9en_US
dc.rightsCreative Commons Attribution 4.0 International licenseen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.sourceNatureen_US
dc.titleRecalibration of deep learning models for abnormality detection in smartphone-captured chest radiographen_US
dc.typeArticleen_US
dc.identifier.citationKuo, Po-Chih et al. “Recalibration of deep learning models for abnormality detection in smartphone-captured chest radiograph.” npj Digital Medicine, 4, 1 (February 2021): 25 © 2021 The Author(s)en_US
dc.contributor.departmentMassachusetts Institute of Technology. Institute for Medical Engineering & Scienceen_US
dc.relation.journalnpj Digital Medicineen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2021-04-06T15:54:37Z
dspace.orderedauthorsKuo, PC; Tsai, CC; López, DM; Karargyris, A; Pollard, TJ; Johnson, AEW; Celi, LAen_US
dspace.date.submission2021-04-06T15:54:39Z
mit.journal.volume4en_US
mit.journal.issue1en_US
mit.licensePUBLISHER_CC
mit.metadata.statusAuthority Work and Publication Information Needed


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