Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests

Author(s)
Davidi, Dan; Fitzgerald, Susan; Glaspell, Hannah L.; Jalbert, Samantha; Klapperich, Catherine M.; ... Show more
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Abstract
Asymptomatic surveillance testing together with COVID-19-related research can lead to positive SARS-CoV-2 tests resulting not from true infections, but non-infectious, non-hazardous by-products of research (amplicons). Amplicons can be widespread and persistent in lab environments and can be difficult to distinguish for true infections. We discuss prevention and mitigation strategies.
Date issued
2021-04
URI
https://hdl.handle.net/1721.1/131118
Department
MIT Medical
Journal
Cell Reports Methods
Publisher
Elsevier BV
Citation
Davidi, Dan et al. "Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests." Cell Reports Methods 1,1 (May 2021): 100005.
Version: Final published version
ISSN
2667-2375
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