Show simple item record

dc.contributor.authorWeaver, Davis T.
dc.contributor.authorMcElvany, Benjamin D.
dc.contributor.authorGopalakrishnan, Vishhvaan
dc.contributor.authorCard, Kyle J.
dc.contributor.authorCrozier, Dena
dc.contributor.authorDhawan, Andrew
dc.contributor.authorDinh, Mina N.
dc.contributor.authorDolson, Emily
dc.contributor.authorFarrokhian, Nathan
dc.contributor.authorHitomi, Masahiro
dc.contributor.authorHo, Emily
dc.contributor.authorJagdish, Tanush
dc.contributor.authorKing, Eshan S.
dc.contributor.authorCadnum, Jennifer L.
dc.contributor.authorDonskey, Curtis J.
dc.contributor.authorKrishnan, Nikhil
dc.contributor.authorKuzmin, Gleb
dc.contributor.authorLi, Ju
dc.contributor.authorMaltas, Jeff
dc.contributor.authorMo, Jinhan
dc.contributor.authorPelesko, Julia
dc.contributor.authorScarborough, Jessica A.
dc.contributor.authorSedor, Geoff
dc.contributor.authorTian, Enze
dc.contributor.authorAn, Gary C.
dc.contributor.authorDiehl, Sean A.
dc.contributor.authorScott, Jacob G.
dc.date.accessioned2021-08-10T17:37:22Z
dc.date.available2021-08-10T17:37:22Z
dc.date.issued2021-07
dc.date.submitted2020-10
dc.identifier.issn1932-6203
dc.identifier.urihttps://hdl.handle.net/1721.1/131160
dc.description.abstractPersonal protective equipment (PPE) is crucially important to the safety of both patients and medical personnel, particularly in the event of an infectious pandemic. As the incidence of Coronavirus Disease 2019 (COVID-19) increases exponentially in the United States and many parts of the world, healthcare provider demand for these necessities is currently outpacing supply. In the midst of the current pandemic, there has been a concerted effort to identify viable ways to conserve PPE, including decontamination after use. In this study, we outline a procedure by which PPE may be decontaminated using ultraviolet (UV) radiation in biosafety cabinets (BSCs), a common element of many academic, public health, and hospital laboratories. According to the literature, effective decontamination of N95 respirator masks or surgical masks requires UV-C doses of greater than 1 Jcm⁻², which was achieved after 4.3 hours per side when placing the N95 at the bottom of the BSCs tested in this study. We then demonstrated complete inactivation of the human coronavirus NL63 on N95 mask material after 15 minutes of UV-C exposure at 61 cm (232 μWcm⁻²). Our results provide support to healthcare organizations looking for methods to extend their reserves of PPE.en_US
dc.language.isoen
dc.publisherPublic Library of Science (PLoS)en_US
dc.relation.isversionofhttp://dx.doi.org/10.1371/journal.pone.0241734en_US
dc.rightsCreative Commons Attribution 4.0 International licenseen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.sourcePLoSen_US
dc.titleUV decontamination of personal protective equipment with idle laboratory biosafety cabinets during the COVID-19 pandemicen_US
dc.typeArticleen_US
dc.identifier.citationWeaver Davis T. et al. "UV decontamination of personal protective equipment with idle laboratory biosafety cabinets during the COVID-19 pandemic." PLoS ONE 16, 7 (July 2021): e0241734. © 2021 Weaver et al.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Nuclear Science and Engineeringen_US
dc.relation.journalPLOS ONEen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2021-08-05T18:36:17Z
dspace.orderedauthorsWeaver, DT; McElvany, BD; Gopalakrishnan, V; Card, KJ; Crozier, D; Dhawan, A; Dinh, MN; Dolson, E; Farrokhian, N; Hitomi, M; Ho, E; Jagdish, T; King, ES; Cadnum, JL; Donskey, CJ; Krishnan, N; Kuzmin, G; Li, J; Maltas, J; Mo, J; Pelesko, J; Scarborough, JA; Sedor, G; Tian, E; An, GC; Diehl, SA; Scott, JGen_US
dspace.date.submission2021-08-05T18:36:20Z
mit.journal.volume16en_US
mit.journal.issue7en_US
mit.licensePUBLISHER_CC
mit.metadata.statusComplete


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record