Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome

Author(s)
Anselmo, Aaron C; McHugh, Kevin J; Webster, Jamie; Langer, Robert; Jaklenec, Ana
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Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/
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Abstract
The gastrointestinal (GI) microbiome is widely investigated for its role in many diseases. However, technologies designed for microbiome delivery are lacking. Here, a layer-by-layer (LbL) approach is reported for probiotic encapsulation to protect probiotics against GI tract insults and improve their adhesion and growth on the intestines. These advantages translate to significantly enhanced survival of LbL-probiotics in vivo.
Date issued
2016
URI
https://hdl.handle.net/1721.1/133345
Department
Koch Institute for Integrative Cancer Research at MIT
Journal
Advanced Materials
Publisher
Wiley
Citation
Anselmo, A. C., et al. "Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome." Adv Mater (2016).
Version: Author's final manuscript
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