Eradicating Bacterial Persisters with Combinations of Strongly and Weakly Metabolism-Dependent Antibiotics

Author(s)
Zheng, Erica J; Stokes, Jonathan M; Collins, James J
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Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/
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Abstract
© 2020 The Authors Zheng et al. rationally combine antibiotics using insights on bacterial metabolism to identify drug-drug combinations that sterilize bacterial cultures of both metabolically active and persister cells, while dose-sparing toxic antibiotics.
Date issued
2020
URI
https://hdl.handle.net/1721.1/133497
Department
Massachusetts Institute of Technology. Department of Biological Engineering; Harvard University--MIT Division of Health Sciences and Technology
Journal
Cell Chemical Biology
Publisher
Elsevier BV
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