Translation Initiation Site Profiling Reveals Widespread Synthesis of Non-AUG-Initiated Protein Isoforms in Yeast

Author(s)
Eisenberg, Amy R; Higdon, Andrea L; Hollerer, Ina; Fields, Alexander P; Jungreis, Irwin; ... Show more
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Abstract
© 2020 The Authors Eisenberg et al. identify translation initiation sites genome-wide in budding yeast. They define a class of 149 genes with alternate extended isoforms that initiate at non-AUG start codons. These isoforms are produced in concert with their corresponding canonical isoforms but typically at lower abundance, and are selectively induced during meiosis.
Date issued
2020
URI
https://hdl.handle.net/1721.1/133749
Department
Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory; Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Journal
Cell Systems
Publisher
Elsevier BV
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